Cheap flights to Mexico from Des Moines

Round trips from Des Moines from $550. Cheapest dates, deal ratings and where to book.

• Cancún: $550, 2026-11-17 to 2026-11-17
• Tapachula: $942, 2026-12-07 to 2026-12-11

Nearby

• Guatemala
• Belize
• El Salvador
• Honduras
• Nicaragua
• United States
• Costa Rica
• Cuba