Cheap flights to South Carolina from Chicago

Round trips from Chicago from $250. Cheapest dates, deal ratings and where to book.

• Myrtle Beach: $250, 2026-12-01 to 2026-12-03
• Columbia: $420, 2026-10-09 to 2026-10-18

Nearby

• North Carolina
• Georgia
• Virginia
• West Virginia
• Tennessee
• Alabama
• Kentucky
• Florida